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我校科研组揭示了剪接变体调控林木次生生长新机制:乐鱼体育,leyu乐鱼体育

发布时间:2023-07-04 00:13:02 点击量:
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木材是木本植物展开次生生长的产物,是最重要的可再生资源,可以用来工业生产和能源生产量。次生细胞壁是木材的最重要组成部分,一系列最重要的mRNA因子参予调控次生细胞壁的构成,有数研究报导NACmRNA因子家族成员Vascular-RelatedNACDomain(VND)和SecondaryWall-AssociatedNACDomain(SND)是参予调控次生细胞壁的构成的关键mRNA因子。本团队2012年在PNAS(http://www.pnas.org/content/109/36/14699.short)报导了PtrSND1-A2的剪辑变体PtrSND1-A2IR作为一个胜调控者诱导了除了PtrSND1-A2自身以外的所有PtrSND1家族成员的传达,因此我们猜测有可能不存在一个不得而知的机制去调控PtrSND1-A2的传达。

本研究对2012年报导展开了先前研究,找到NACmRNA因子家族成员PtrVND6-C1不存在一个功能互为类似于的剪辑变体PtrVND6-C1IR,PtrVND6-C1IR可以诱导PtrVND6家族所有成员的传达除了PtrVND6-C1。此外,我们还找到PtrVND6-C1IR和PtrSND1-A2IR同时可以作为胜调控者交互调控PtrSND1和PtrVND6成员的传达,即PtrVND6-C1IR在诱导PtrVND6家族成员的同时还可以诱导还包括PtrSND1-A2在内的所有PtrSND1成员;某种程度PtrSND1-A2IR可以诱导还包括PtrVND6-C1在内的所有VND成员。

以上试验结果表明在林木发育的过程中,不存在PtrVND6和PtrSND1家族成员的剪辑变体交互调控PtrSND1和PtrVND6家族成员传达的新机制。这种新机制有可能作为一种广泛的现象不存在于NACmRNA因子家族以及其他mRNA因子家族,同时阐述了剪辑变体潜在的新功能。本研究获得了国家大自然基金委大自然基金重点项目的反对。


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